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Epistemology of the Cell: A Systems Perspective on Biological Knowledge (IEEE Press Series on Biomedical Engineering)
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Review
“The authors of this interesting and opinionated book state that the driving force behind the work was Einstein’s comment that “science without epistemology is–insofar as it is thinkable at all–primitive and muddled . . . The last chapter of the book is an excellent exposition of the need for a systems-level model-based approach in biology and medicine.” (Computing Reviews, 19 February 2013)
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About the Author
EDWARD R. DOUGHERTY, PhD, is Director of the Genomic Signal Processing Laboratory at Texas A&M University, where he holds the Robert M. Kennedy '26 Chair and is Professor in the Department of Electrical and Computer Engineering. He is also co-Director of the Computational Biology Division at the Translational Genomics Research Institute as well as Adjunct Professor in the Department of Bioinformatics and Computational Biology, M. D. Anderson Cancer Center at the University of Texas. Dr. Dougherty has published more than 300 peer-reviewed journal articles and book chapters. MICHAEL L. BITTNER, PhD, is co-Director and Senior Investigator at the Computational Biology Division at the Translational Genomics Research Institute. Previously, he was associate investigator in the Cancer Genetics Branch of the National Human Genome Research Institute at the National Institutes of Health. Dr. Bittner holds a dozen patents and has published more than 100 articles.
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Product details
Series: IEEE Press Series on Biomedical Engineering (Book 34)
Hardcover: 216 pages
Publisher: Wiley-IEEE Press; 1 edition (August 30, 2011)
Language: English
ISBN-10: 1118027795
ISBN-13: 978-1118027790
Product Dimensions:
6.3 x 0.7 x 9.5 inches
Shipping Weight: 1 pounds (View shipping rates and policies)
Average Customer Review:
5.0 out of 5 stars
3 customer reviews
Amazon Best Sellers Rank:
#5,349,995 in Books (See Top 100 in Books)
The book, Epistemology of the Cell, by Dougherty and Bittner, is a gem. Dougherty is a Professor at Texas A&M and has written extensively and brilliantly on the issue of using systems thinking in the growing field of genomics. Now systems thinking was, in way, started by Norbert Wiener in the 1930s, as he began to model various systems, from the dynamics of nerve fibers to the development of the first artificial arm. Yes, he did the arm, not the physician at Mass General. Wiener also developed the systems to the control the pointing of radar controlled guns on ships in WW II.What made Wiener unique was that Wiener asked "Why". The why meant finding the cause and the result and establishing the connection between the two, establishing the system. Physicists and chemists ask "why" questions, the find the cause and the causality chain. Biologists were for ages asking "what" as people who classified.Darwin broke that chain of biologists somewhat by asking "why" as regards to evolutions and he is pilloried even to this day. Physicians often ask "what" and "how" and do not really want to be bothered by the "why". It is not their jobs to find out why, just find out "what" is wrong and know "how" to fix it. Thus a physician is taught "what" to look for to diagnose prostate cancer and is also taught "how" to remove it. The physician does not know or care "why" the cancer is doing what it is doing. That is epistemological.That, in essence, is a simplification of what Dougherty and Bitter go about to explain. Their book explores the challenges set forth to those exploring the gene and the cell and entices them to think beyond just the what and how to go to the why, the explanation of the process, the system, from cause to effect. The authors have written a treatise which compares a few others which look at the epistemological basis of research, asking the correct questions, and pursuing the best path to answer them (see the work by Winograd and Flores Understanding Computers and Cognition: A New Foundation for Design as a prime example written some 25 years ago). Dougherty has with his colleagues and associate been developing the ideas contained herein for well over the past decade and I have read many of his works, they provide great insight to what should be done.Chapter 1 begins with a discussion of the definition of epistemology, on p. 2. They define scientific epistemology by what it addresses; knowledge and its truth. Then they use Kant to develop the transition from the Enlightenment to today. On p. 4 there is a brief but focusing discussion where he explains the simple Newtonian world maturing into an Einstein one and likewise a Watson and Crick paradigm of DNA/RNA/proteins into the way we understand cell dynamics today, as pathways, miRNAs, repressor enzymes and the complexity of both intracellular dynamics and intercellular dynamics. They rely extensively on a Popperian view of Science, which for those more familiar with Kuhn may tend to have some slight dissonance, but it holds together quite well.All in all, Chapter 1 sets the stage well, both from establishing the necessity to have models which answer why, and to establish the counterpoint of the thinkers who have reverted back to Aristotelian classification as the finders of what.Chapter 2 is a discussion of Aristotelian causality. p 14 states it well with the statement,"explanation must involve a causal relation...".On p 21 they state, "Galileo and Newton do not deny causality as a category of knowledge but they widen the scope of knowledge to include mathematical systems that relate phenomena, while bracketing "questions about nature" of the phenomenon...".On pp 33-34 they have an excellent discussion of Bertrand Russell's work on causality.In Chapter 4, on p 70, the authors use the work of Norbert Wiener and his associate Arturo Rosenbluth on Cybernetics Cybernetics, Second Edition: or the Control and Communication in the Animal and the Machine. For it was indeed "the synergy of communications, control, and statistical mechanics..." that set the framework of how we should view cellular and organ dynamics. The authors then given examples of gene regulation. I would have simply stated that every cell and every organic system is a multidimensional distributed random process.One could take a Feynman like approach and posit the obvious, and then fill in the details. The authors work from the bottom up to demonstrate their world view. Namely that when we look at cells we are looking at complex dynamic random systems. Systems we can ascribe states to, states being measurable quantities, which in turn operate on other states in a dynamic fashion.In Chapter 5 the authors start the transition to complex state models. They again rely on the wisdom of Wiener on p 89 to state:"Wiener recognized the difficulties that the mathematical requirement of science and translational science would present for medicine ..."For back in 1948 when Wiener had published Cybernetics, Medicine was still a "what and how" practice. It did not transition to a "why" approach. The translational science that the authors speak of is:"... mathematical engineering, applied mathematics with a translational purpose.."Namely, to translate nature to measurable quantities. Quantities which we can then by knowing the "system" we can then manipulate and predict. We can observe and we can control, the end goals of translational science. In a Popperian sense, the authors address the issue of measuring, predicting, and examining what does not do what we said it would.The key arguments are developed in Chapter 9 and 10. Chapter 9 is the "sola fides" discussion, faith alone, as a mantra to those who fail to understand the system nature of the cell dynamics. The authors, on p 149, evoke William Barrett, the insightful Columbia University philosopher, who wrote The Illusion of Technique The Illusion of Technique , a superb work integrating the principles of epistemology and science in the late 1970s. Frankly, to see Barrett in a book of this type was an exciting surprise, for I had thought that Barrett was falling into obscurity, a loss to many who are struggling with issues that Barrett has thought through decades ago. The authors then on p 148 also discuss the nature of stochastic dynamic systems.Dougherty brings insight via avenues that I found resonated strongly. The discussion on Wiener, where Dougherty, unlike Gleick in what I feel is presented with uninformed bias, sees Wiener as the father figure, one combining systems thinking, clear and built upon strong mathematical foundations, which is then integrated with real biological systems. Although I find their approach insightful and compelling, I would have taken pathways in cancer dynamics as somewhat well-defined stochastic systems.For example, we know the effects of PTEN, the AKT pathway, and the MYC pathway, the p53 pathway, and the complex dynamics which are well described in the readily available NCI data base of pathways. One can use as states the concentrations of any one of these proteins and then state simply that they all interact with one another, the result being homeostasis or if a change cancer. The model is multidimensional, stochastic, highly complex, and strewn with "noise", namely uncertainties. Models have been developed and tested for such cancers as prostate, melanoma and colon. Dougherty, himself, has made substantial contributions to this area. It would have been useful perhaps to demonstrate this approach as well.On p. 163 the authors place a stake in the ground to say what would be expected for those to work in the field, that the books by Loeve Probability Theory I (v. 1) and Cramer Mathematical Methods of Statistics. (PMS-9) be used as standard bearers! As I read that in the book I looked on my bookcases and saw my old well-worn copy of Loeve, which got me through my PhD. Cramer was my core text for my introductory course, but then again it was MIT. Thus they set a high hurdle, but a necessary one for those to work in the field. My first book, Stochastic Systems and State Estimation (Wiley, 1972) Stochastic Systems and State Estimation, in a sense was one of the many which established the bar.The clear strike at the adversaries is set on p. 165. After again referring to Barrett and Kant, the authors end with:"Does anyone really believe that data mining could produce the general theory of relativity?"I think this can be extended. For example many researchers run millions of microarrays and are currently finding hundreds of SNPs or thousands of miRNAs and each time they send out a press release saying they have "discovered" some new "gene" or worse "cause" or "cure" of say prostate cancer or melanoma. In reality one does not know whether this is a marker for cancer, a marker for a predisposition for cancer or just plain noise.What the authors, and others, have argued is that it is essential to have a well-defined dynamic system model of how say PTEN and AKT interact and how they in turn control MYC and where the controls on p53 are in this chain. The microarray analyses should be done in the context of defining the linkages in the state model and not as ends in themselves. The model can then be validated. From such a model we can then see conditions on their way to cancer and conditions representing advanced cancers. For example, recent authors have announced a way to measure PTEN in prostate cancer and laud that as a diagnostic step. In reality by the time PTEN has been deactivated there is most likely a metastasis. Understanding and refining a model is the essence of the "why" articulated by the authors.On p 166 there is a superb critique of what the authors call the pre-Galilean thinkers, namely the biologists who like Linnaeus were really just classifiers of forms and shapes failing to understand why they were what they were. One must remember that biology was all too often just a study of things and a process of naming them and classifying them. The systems which made for these differences were little understood, and worse, beyond the mindset of many who practiced in the field.Chapter 9 is. in my opinion. the pinnacle of their argument. Simply put, we should now begin to perform our experiments within the context of a model. For example, we know many of the pathways of the key genes intracellular, but we do not yet understand the dynamic model that controls them. Thus, when we do microarray tests, we should be doing them to determine the constants in the model and then validate that design. We should, in effect, identify the system, using a system framework, not just some unstructured set of classifiers. We have the structures, now is the time to put them to use.Science is iterative. It is an iterative set of models and refinements. On p 171, the authors refer to Turing's last paper on tessellation, or why zebras have stripes. The paper by Turing was submitted a day or two before he committed suicide and it was done without the benefit of Watson and Crick who were simultaneously doing their work at Cambridge. He intuited intercellular flow of some yet to be defined controlling substances. The concentration of these unknown substances would rise and fall in concentration and as such the color would change.This approach has recently been applied, using a system model of flower genetics, and it explains and demonstrates the control of patterning in a genus of flowers. Having the model for this genus of flower, which is experimentally verifiable, one can then do the inverse, namely the controllability issue of creating desired flower patterns. That also is the essence in cancer dynamics, namely of creating a control or cure, but with a verifiable model. One must have the model, thus say the authors. Thus says nature! If one takes the authors systems approach and applies it to intercellular systems thinking, then it can be argued that the stem cell of cancer theory as has been recently evoked can be readily explained, as readily as those zebra stripes! That is the strength of the model posited by the authors.My only negative is the price. There are some 187 pages and the price is well above $100. Amazon does have a better price but not much. That is over $0.60 per page, and for that I would blame not just Wiley, but the IEEE, which somehow has all too inflated prices. This book is so insightful that the barrier to entry should be more modest. However, it is worth the insight at any price however.And one last nit. The work of the authors should also shine a light on macroeconomics, which suffers not from a surfeit of models and mathematics, but from any ability to validate them, just look at the current state of the economy. Thus what biology brings from data to systems, macroeconomics brings from systems to reality. Both have to merge and be able to be predictive. We are approaching that in biology, especially with the insight of the authors, it is a pity that such has not yet passed the minds of those who opine on the world's workings.
[For full disclosure, the reviewer is a colleague and personal friend of one of the authors.]This book is a philosophical disquisition on the Epistemology of Science, as it relates to the interface between Engineering on one hand, and Biology and Biomedicine, on the other. The book is written by two accomplished scientists: a Mathematician (Dougherty), with a long career in the Engineering, and a Biologist (Bittner). These distinct backgrounds reflect the multidisciplinary foundation of the book.The philosophical outlook of the book is that of the revolutions in Science and Engineering that occurred in the first half of the 20th century, including Einstein's Relativity Theory and Quantum Mechanics in Physics, as well as the views of Biologist Conrad Waddington and Engineer Norbert Wiener, both of whom advocated a Systems approach to Biology. The authors argue that this epistemology, based on a positivistic/idealistic framework, is the final, mature foundation of science, which is the outcome of a long process that began with Galileo and Newton. The authors argue that Biology will become a successful, mature science only if it adopts this same epistemological view of science. The book supports its viewpoint with many famous quotes by eminent scientists throughout the text.A brief outline of the book follows. Chapter 1 introduces the main epistemological framework of the book, stressing an idealistic view, based on mathematical modeling and prediction, as opposed to a realist view, based on "everyday" explanation. It also emphasizes the limits of Science, and its pragmatic nature. It likens the current state of Biology to that of Physics at the end of the 19th century, and argues that Biology can only make the leap to a mature science if it can resolve the same epistemological conundrums that Physics had to face in the early 20th century.Chapter 2 is a comprehensive discussion of the evolution of the concept of causality in philosophy, from its beginnings in Aristotle through its definitive (according to the authors) formulation, proposed by Hume, going through the views of Francis Bacon, Galileo, Laplace, Kant, Mill, Einstein, Russell, and Reichenbach. This is important to the book, the authors argue, as the pre-Galilean view of Science (combated in the book) had as a distinguishing feature a naïve realist view of causality.Chapter 3 focuses on the scientific method, and its evolution from its beginnings in the ancients through modern 20th century Physics. It emphasizes the role of the controlled experimentation and prediction, a breakthrough credited to the early modern scientists, such as Bacon, Galileo and Newton, and of Mathematics as the proper language of scientific knowledge. It classes the concept of "explanation" as rationalistic and as an impediment to modern science: explanation, as causality, must remain outside the arena of scientific discussion. This chapter emphasizes again that Mathematics is the proper, and the only safe, language of science. Finally, it highlights the importance of an epistemology including uncertainty (expectation) as opposed to a deterministic epistemology (based on causality).Chapter 4 discusses the abstract regulatory processes of the cell as the essence of the "secret of life," as opposed to the mere physicochemical components that implement them; in this way, biology is separate from physics and chemistry. This is a "systems" view, first proposed by Waddington, as the authors point out. From this, the authors argue that this essential component of the living cell must be modeled as a stochastic dynamic system, with the accompanying issues of synchronicity, fault tolerance, and parallelism present in physical plants. This chapter requires some mathematical sophistication from the reader in its later sections. It discusses the important notion of canalizing genes, and goes on to survey briefly the "master-slave" model, intervention in probabilistic regulatory networks, and the "intrinsic multivariate prediction" phenomenon, all studied by the authors in previous scientific papers. Finally, the material of the chapter is analyzed from the epistemological perspective outlined in earlier chapters.A definition of translational (applied) science is given in Chapter 5. Translational science is identified with synthesis, as opposed to "pure" science, which is concerned with analysis. Synthesis is then identified with the modern engineering approach of Wiener and others. A wonderful quote by Wiener (page 91) summarizes the need for truly multidisciplinary teams in translational science, a goal that is still mostly a prospect at the present time. The discussion is supplemented by an example involving the external control of Boolean regulatory networks.Chapters 6 and 7 are the most technical in the book, dealing with the concept of stochastic validation in pattern recognition (classification), and in the inference of regulatory networks, respectively. Chapter 6 also includes a discussion on the need of a stochastic approach to describe physical systems, and how this can be done using conditional expectation. It also discusses the need of modeling assumptions for validating classifiers (and indeed, in translational science in general). Chapter 7 deals with some of the same issues of validation and performance, but this time for the much more complex case of network models.Chapter 8 is a somewhat acid critique of the current subjectivist and relativistic currents observed in much of 21st century Science, using for that the particular perspective of unreliable methods for classifier error estimation. It starts by reaffirming the overall epistemological viewpoint of the book, through Hume and Kant, and then proceeds to give specific examples relating to classification error estimation, showing that there can be large variances and no correlation between estimated and true errors. In an interesting twist, the authors compare belief in these techniques to the exhortation to believers, made by early protestant leaders, to rely on faith alone (sola fides = faith alone or, more to the point, "blind faith"). This is followed by warnings on the "illusion of technique" offered by modern computer technology (this is, incidentally, in no way a luddite manifesto) and the attempts of expanding the scope of the scientific method to suit one's desires.Finally, Chapter 9 is an essay on the limited prospects of medical intervention in the absence of a systems approach, citing many examples to support this view, and thus returning to the main theme of systems biology proposed by the book.
Two of the leading figures in translational genomics and computational systems biology, Dougherty and Bittner have taken on a subject that is at the very core of modern biology. Evoking Wiener and Rosenblueth, the authors draw on their own immense experience in systems theory and engineering, molecular biology and biochemistry, to guide the reader through foundational issues that, if ignored, stand squarely in the face of progress in biology and medicine. This elegantly written book is unique in its scope while achieving the depth that the subject matter deserves. Every systems biologist ought to read this book.
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Push past the man's rightly-earned bitterness and his passion for the old shoot-style that younger audiences may find a little boring, and you get an entertaining and informative glimpse into the management side of the business.Having grown up watching NWA wrestling from the '70s-'80s and comparing it to today's product, there's just no comparison. NXT's dimly-lit arenas are close, but no cigar. WWE continues to fuel my suspicions that the combined attention-span of its creative writing team is all of 15 minutes. Some of the key points Ole makes in this book:Just because a movie or TV show is fake doesn't mean you have to keep reminding your audience, and it doesn't mean that it doesn't take talent or skill - not only from the actors but also from the writers and directors.Wrestling was once so entertaining that it got real heat - so much so that heels like Ole would be physically attacked by fans. I can't imagine today's product getting a fan riled up enough to even buy a ticket to come back the following week, let alone try to stab a 300-pound wrestler!Numbers don't lie. WWE/F can brag all they want about revenue, but they didn't fill the same arenas week after week like Ole's promotions did. A weekly entertainment budget of $15 was no small amount for a blue-collar family of four during the late '70s to early '80s, so your shows had to be entertaining and the storylines long enough to keep them coming back.Thank you Ole, for the great wrestling, booking and now, this book!
Don't ask Ole. At first when I started reading I thought what a bitter person and I wasn't sure I was even going to finish. After reading over 15+ autobios from different individuals in the pro wrestling industry, it is hard to challenge what's stated in this amazing life of 1/2 of the wrecking crew. Ole is spot on and as bad as I hate to admit it, his opinions apparently are also factual. I'd highly recommend if you want it told like it is.
Either Ole Anderson was the smartest guy in wrestling, or he is the largest egotist of all time.(read prick) It's a good read, Ole was there in the 70's, 80's 90's and into the 2000's, he has literally seen it all and seems a bit bitter about it. After the fall of WCW it is pretty easy to see that the Bischoffs and Herds of the organization screwed up in huge ways, David Arquette, REALLY? I enjoyed Ole's stories and I enjoyed the inside look into the GCW and Mid-Atlantic days. Ole glories in telling others to kiss his ass, and then go on to prove they should, either way the book is enjoyable.
Listen up. No one in the world of Professional Wrestling is more knowledgeable and to the point than Ole Anderson! It is a blessing that Ole has chosen to share his insight with us! He may come off at times like an arrogant bully but If there were a lot more men in the wrestling business like Ole Anderson we would all have a far superior sport to enjoy! If you are a real fan of Professional Wrestling you must get this book!!!!!
I always enjoy reading books about the behind the scenes activity that went on in professional wrestling. Some of the other reviews seem to think that Ole Anderson is full of himself but I really feel like he tells it like it is.
Ole Anderson is the biggest fan of Ole Anderson. He will give some self criticism but that’s only for modesty reasons. The book however is very enjoyable. What should be a warning it is mostly about Ole’s career as a booker, so there is not much about his famous turn on Dusty and almost nothing about four horsemen.Ole’s views on wrestling are really old school but there is a lot of insight and it read really well.
Ole Anderson puts it right into perspective (as he always does)!!!!
While I agree with other reviewers that there should have been much more about the 4 horseman , I still feel like this was one of the better books regarding pro wrestling .Thank you Ole for telling it like it is. I relieved many memories as a child watching pro wrestling on Mid Atlantic and of course on TBS.
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Let's Make a Memory, by Gloria Gaither Shirley Dobson
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Product details
Paperback: 224 pages
Publisher: W Pub Group; Revised edition (November 23, 1994)
Language: English
ISBN-10: 0849935172
ISBN-13: 978-0849935176
Product Dimensions:
8.5 x 0.8 x 11 inches
Shipping Weight: 1.4 pounds (View shipping rates and policies)
Average Customer Review:
4.6 out of 5 stars
12 customer reviews
Amazon Best Sellers Rank:
#178,480 in Books (See Top 100 in Books)
This has great ideas, scripture reference and loads of ideas for parents to lead activities with young children.The book seems a bit dated but it's filled with a wealth of ideas. Maybe a modern version of this book needs to be published with pictures of actual products or in color.All in all, it's a fair book.
Excellent family book which I gave as a gift to an expectant mom. This book should be republished as it's the kind of book people need in this difficult time we are all going through. I have given it several times to new parents or at baby showers.Georgiann
I'm not a big Gaither fan but when my kids were little I read this book and got all kinds of good ideas. For example, we interviewed our kids on tape every birthday. Now that they are teenagers, these tapes are a real treasure. I highly recommend this book for young families who want to start some cherished family traditions.
This is a great resource book for anyone who has children or grandchildren and they also make great gifts! Shipping was excellent.. I believe I received it in a days time!
Great book! Lots of fun ideas.
I bought this book 28 years ago when both of my children were small. I loved it and am now giving one to my daughter and her baby. I know she will enjoy it as much as I did.
love this book - lots of ideas for starting & celebrating family traditions
"Let's Make a Memory" is an old favorite. Many wonderful ideas that are easy to do or will inspire you to come up with your own ideas.
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Download PDF OS X and iOS Kernel Programming
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OS X and iOS Kernel Programming
Download PDF OS X and iOS Kernel Programming
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Product details
Paperback: 484 pages
Publisher: Apress; 1st ed. edition (December 23, 2011)
Language: English
ISBN-10: 1430235365
ISBN-13: 978-1430235361
Product Dimensions:
7 x 1.1 x 10 inches
Shipping Weight: 2.3 pounds (View shipping rates and policies)
Average Customer Review:
2.9 out of 5 stars
5 customer reviews
Amazon Best Sellers Rank:
#917,377 in Books (See Top 100 in Books)
Completely skips anything video related. Might better be called: "OS X and iOS USB & PCI Drivers Kernel Programming". The parts that are included are not bad though.
The word "kernel" programming maybe a bit of an overstretch. This is a book on IOKit -- the only real part of the kernel Apple allows you to make changes too.Still, I really liked this book. There is clarity of thought in the explanations in the book. The examples are appropriately short and interesting.
I was actually surprised how much I liked this book. It does an excellent job of collecting all of the scattered information about Apple device drivers. Granted, most of this information is available elsewhere, but it can be difficult to find in one location, and Apple's technical documentation is notoriously incomplete.
I am not complaining about the content of this book, but its quality.I brought this book in May, 2016, and read several pages per day after work. Today, I suddenly find that pages from 175 to 274 are missing, and I cannot even get it exchanged. I am very disappointed about it, and I don't want to buy another copy.
First of all "OS X and iOS Kernel Programming" is basically the second book on the development in xnu kernel environment, the first being of course Amit Singh's wonderful "Mac OS X Internals". While Amit's book is more of a greatly detailed overview of the inner functioning of the xnu kernel the "OS X and iOS Kernel Programming" deals more with the practice of kernel development, at least this is my impression. Based on that i find only one big flaw with this book: incomplete coverage. This is really a book about IOKit driver development. BSD file system drivers, KAuth framework, sysctl, etc. is only very briefly mentioned if at all. This leaves a huge gap in the overview since those are integral parts of the Mac OS X kernel. More minor flaws basically have to do with coding examples and lack thereof. This book can greatly benefit with the more complete examples since most of the early chapters often end the discussion abruptly without having shown the full application of the topic in practice.Nevertheless this book succeeds in a more practical and rarely discussed topics such as kernel debugging, driver deployment, file IO from the kernel, user/kernel notifications and memory mapping, thread management and user land interaction, device DMA. The IOKit focus of the book also let the authors describe a lot of device driver types. All in all this is in my opinion a long needed book to fill the gap on practical issues of xnu kernel development and i greatly enjoyed reading it. I recommend it to anyone beginning the IOKit driver development.
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Download PDF National Geographic Kids Almanac 2018 (National Geographic Almanacs)
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National Geographic Kids Almanac 2018 (National Geographic Almanacs)
Download PDF National Geographic Kids Almanac 2018 (National Geographic Almanacs)
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From School Library Journal
Gr 3–7—National Geographic's titles are browsable and entertaining, and this almanac is no exception. It touts that it includes "everything you always wanted to know about everything." That's a big claim, but kids will find more than 500 color photos and tons of fun facts on a wide range of topics, such as animals, "going green," science, engineering, and pop culture. The entire book is a trivia quiz waiting to happen. Need to know 18 facts about fungi? They're here. So are introductions to well-known authors and scientists, a look at 3-D printing, and a sneak peek at major events coming in 2018, such as the Winter Olympics. While there's a chapter devoted to games, jokes, and puzzles, there is plenty of substance here, too. And a link to extra content may prompt readers to seek out more online. VERDICT Buy several; this book will likely see a ton of browsing.—Sharon Verbeten, Brown County Library, Green Bay, WI
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About the Author
NATIONAL GEOGRAPHIC KIDS inspires young adventurers to explore the world through award-winning magazines, books, website, apps, games, toys, television series and events and is the only kids brand with a world-class scientific organization at its core.
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Product details
Age Range: 8 - 12 years
Grade Level: 3 - 7
Lexile Measure: 1040L (What's this?)
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Series: National Geographic Almanacs
Hardcover: 352 pages
Publisher: National Geographic Children's Books (May 9, 2017)
Language: English
ISBN-10: 1426327730
ISBN-13: 978-1426327735
Product Dimensions:
6.3 x 0.8 x 9.3 inches
Shipping Weight: 1.7 pounds
Average Customer Review:
4.7 out of 5 stars
63 customer reviews
Amazon Best Sellers Rank:
#825,014 in Books (See Top 100 in Books)
Put the same book back at big box store and ordered right then and there to save $. Plus my 8 year old loved receiving a package from Amazon addressed to him. A fan favorite NG book we will definitely buy every year!
My 8 year old is a bit of a book nerd and these books have become a ritual for us. Every couple weeks we add another to his collection and this was a preorder for us that turned out to be a great investment! Every day he has some new piece of information to share that often leads to more curiosity and questions. Would definitely suggest all of these if you have a curious kid!
This is a very informative book for kids and adults. I'm seeing my grandson picking it up to read and get so interested it what he's reading forgets what he doing. I have 3 years of almanacs and they are always being picked up by someone to read. I recommend this book for boys and girls, has a lot of information that is interesting
I love this book. My children love this book, too. That's why I bought a new version each year.This year I placed the newest version in the goodie bags for my son's birthday party. Most of the children couldn't wait; they started reading right away. Some parents later told me that this book was the best goodie their children ever had.
Its Nat Geo and my kids loved it! So many facts and gorgeous pictures all packed in one that make reading fun. Size is not too big or too small. We will be purchasing these every year! My kids are learning and reading without even realising it! LOVE LOVE LOVE!
Yes, kids will enjoy it, but so will adults. An example: Do you know that the earth travels around the sun at a speed that's 100 times that of a jet plane? There's interesting information for people that have a sense of curiosity.
This has kept my 9-year-old grandson entertained for hours. A lover of "factoids," there are plenty of interesting things to learn in this almanac. Great National Geographic quality.
Our 7.5 year old loves this and keeps pouring over all the facts. Keeps her occupied for hours on end.
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PDF Download No Excuses: The True Story of a Congenital Amputee Who Became a Champion in Wrestling and in Life
PDF Download No Excuses: The True Story of a Congenital Amputee Who Became a Champion in Wrestling and in Life
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No Excuses: The True Story of a Congenital Amputee Who Became a Champion in Wrestling and in Life
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Audible Audiobook
Listening Length: 5 hours and 3 minutes
Program Type: Audiobook
Version: Unabridged
Publisher: Regnery Publishing
Audible.com Release Date: July 5, 2012
Whispersync for Voice: Ready
Language: English, English
ASIN: B008I532A4
Amazon Best Sellers Rank:
I was really excited about this book. Kyle's story is very inspirational - not letting anything get in his way of achieving his goals. When I started reading, however, I became less and less enthralled. While the story is still impressive, the telling was lacking. The writing was somewhat simplistic, and the organization makes the story hard to follow. He jumps around chronologically, making it difficult to follow the progression of his struggles and triumphs. Some of his points are repeated many times in more or less the same language. In all, I only made it through about half the book before I lost interest in wading through for the few glimmers of inspiration buried deep down.
Five stars for a worthy story of one human among us but zero stars for the writing. Steel yourself for atrocious writing and then remind yourself throughout the book that you are reading it to learn of this young man's life and not for the writing -- and you may be able to appreciate and benefit from it. I apologize for my own shortcomings in having trouble getting over the writing - but I found it really horrendously bad - like a first draft from an 8th grader (again, I'm sorry to say this). I found myself distracted throughout by the lack of editing and the repetitive thoughts. I wish someone would have encouraged the young author to have an editor review the manuscript, because the story, nonetheless, is a worthwhile read.It's a simple book, so read it for just that. Kyle does not write with a maturity that comes with understanding how to express the emotions that drive him beyond just the raw, primordial impulse by which he is driven in his life to live with no excuses. And he doesn't allow us into his soul to understand how a man so young has learned to shut out doubt every day. At writing, he is still a youth who perhaps has not taken time yet to delve deep enough to put in writing his emotions.It is a short, very quick read - large type with lovely photos. An easy 2-hour read. I recommend this book for grades 5-8.
Even before you get very far into this book, you feel a strong closeness to Kyle. His examples and his sayings are tremendous. A great read and an enjoyable book. It takes me a month to read a book and I finished this one in a few days. GOD BLESS KYLE!
Very great story. It's one thing to tell a kid that they can do anything they put their mind to when they're born with a body that's not "normal".But it's another thing for a man like Kyle to SHOW people that it's possible. He's served as an inspiration to at least 2 of my patients and their families, because they can see the possibilities of life as an adult, defining and projecting who you are as a man, rather than letting society tell you who you are supposed to be.Excellent read. Highly recommended.
Very motivating story, got it for my granddaughter who will be in a wheelchair temporarily from car accident to encourage her.
It’s an easy read that will keep you fully engaged from chapter to chapter. However, don't read this book if you're intending to stay where you are in life. Once you see what Kyle has achieved, overcoming the challenges he has faced, the book is truly appropriately titled. And its message will hit home with you as it did me. We all are exactly where we’ve chosen to be. And so, in the end, the book is really not about Kyle at all. It’s really about all of us, and it’s time to choose differently … with no excuses!
Great product and service!
This book is a fantastic read for anyone stuck the least bit in self pity. I am a cancer survivor and reading this book helped to put things in perspective. Painful realities like Neuropathy can become too large of a focus and hence a limitation. I feel much better and more in control of my life after reading this special book. Too often, people let things which can be overcome become a wall instead of a challenging hurdle. For those of you who did not wrestle in High School this could be a long read. I encourage you to relate his love of wrestling for any passion you have felt in your life. This is an excellent book from a young man of few years and yet he has worked hard and gained a wealth of wisdom. I commend Kyle Maynard and his exceptional book. You will gain much in reading this book. Tad O. Patterson
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PDF Ebook The God Who Sees: Immigrants, the Bible and the Journey to Belong
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The God Who Sees: Immigrants, the Bible and the Journey to Belong
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Review
"Karen González weaves together a brilliant book that illuminates how central the stories of immigrants are to the story of God. This is true not just in the Scriptures but also today, as Karen beautifully illustrates when she describes how God drew her close. Immigration is often talked about as a policy or political issue, and this book is a sorely needed reminder that immigration is a personal issue--one that can connect us all to the heart and mission of God."--Jenny Yang, vice president of advocacy and policy at World Relief and coauthor of Welcoming the Stranger"With this stunning debut, Karen González makes her mark as one of the most talented storytellers of faith in a generation. The skill with which she weaves together personal narrative, biblical text, intimate detail, and sociopolitical analysis is as impressive as it is seamless. Every single page of this beautiful, timely book pulses with prophetic truth. It left me changed in all the best ways." --Rachel Held Evans, author of Inspired and Searching for Sunday"We are changed by whom we read the Bible with. The God Who Sees is an invitation to read the Scriptures with the fresh eyes of Karen González, a theologian with a story that is relevant, heartbreaking, and always surprising. González deeply believes in the God who sees, and she invites her readers to discover the God who is obsessed with the immigrant. In a time of fear, The God Who Sees is a powerful testimony to what makes the good news actually good." --D. L. Mayfield, author of Assimilate or Go Home"The God Who Sees artfully weaves theological application and immigration policy and practice, inviting the reader to engage more deeply in important justice issues of today. At a time in which numerous voices are being pushed into the immigration narrative, Karen González's perspectives as a theologian and Latina immigrant, straddling Guatemalan and American cultures, are both insightful and impactful. Thank you, Karen, for sharing your heart, your mind, and your voice in this book. It is a gift." --Michelle Ferrigno Warren, activist and author of The Power of Proximity"The topic of immigration can be both confusing and contentious. Karen González helps us find our way toward a deeper understanding with The God Who Sees, a story that is deeply personal, solidly biblical, and appropriately challenging. You will find Karen González an able guide to bring clarity and encourage compassion." --Scott Arbeiter, president of World Relief"Weaving insightful reflections on the stories of immigrants in the Bible, compelling explanations of the realities facing immigrants today, and her own testimony of faith and migration, Karen González invites readers into a distinctly Christian approach to the complex topic of immigration. In the process, she invites us into a deeper relationship with the God who made and loves them. The God Who Sees is an important and enlightening book for our times." --Matthew Soerens, coauthor of Welcoming the Stranger and Seeking Refuge"In this engaging book, Karen González skillfully weaves her narrative with the biblical narratives and insightful comments on current immigration realities. This slim volume is a helpful introduction for those who want to love their immigrant neighbors. I appreciated the action and reflection questions that end the book and offer helpful next steps." --Jude Tiersma Watson, associate professor at Fuller Theological Seminary"What does it mean to surrender our lives to the God of the immigrant and stranger? That question feels more pressing than ever in our modern times. The God Who Sees takes us on a journey that brings us to the heart of God and shapes a new way of seeing the world. Trust the leadership of Karen González, an important spiritual guide for these critical conversations." --Daniel Hill, pastor and author of White Awake"The God Who Sees is the book I have been waiting for: a Christian book on immigration, written from the perspective of a Latina theologian and ministry practitioner, that centers the voices and experiences of our Latino community. It is like refreshing water to my soul. Karen González stands at the vanguard of a rising generation of Latina/o Christian authors whose voices are critical for the healing of the church in America." --Robert Chao Romero, professor of Chicana/o studies at UCLA"The God Who Sees offers the powerful combination of an immigrant experience expressed through the lens of Scripture. Nothing can be more compelling for those who claim the Christian faith. As a fellow Guatemalan American, I resonate with this book that brings to mind my own memories and their emotive power. Karen González's voice is gentle, yet forceful, and needs to be heard--along with those of millions of others!" --M. Daniel Carroll R., professor of Old Testament at Wheaton College and author of Christians at the Border
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About the Author
Karen Gonzalez is a speaker, writer, and immigrant advocate who works as training and development manager for World Relief. An immigrant from Guatemala, Gonzalez has an MDiv from Fuller Theological Seminary. She has worked in the nonprofit world for more than ten years and is a former public school teacher. Gonzalez, who lives in Baltimore, has written for publications including Sojourners, Christ and Pop Culture, Faithfully Magazine, Mutuality Magazine, The Mudroom, and The Salt Collective.
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Product details
Paperback: 232 pages
Publisher: Herald Press (May 21, 2019)
Language: English
ISBN-10: 151380412X
ISBN-13: 978-1513804125
Product Dimensions:
5.2 x 8 inches
Shipping Weight: 1.1 pounds (View shipping rates and policies)
Average Customer Review:
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Amazon Best Sellers Rank:
#552,169 in Books (See Top 100 in Books)
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